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You must drink plenty of water to prevent additional clots while on warfarin coumadin.

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Prothrombin complex concentratePCCfresh frozen plasmaor activated Factor VII treatment may be considered if the requirement to reverse the effects of COUMADIN is urgentA risk of hepatitis and other viral diseases is associated with the use of blood productsPCC and activated Factor VII are also associated with an increased risk of thrombosisThereforethese preparations should be used only in exceptional or life-threatening bleeding episodes secondary to COUMADIN overdosage.

COUMADIN is a racemic mixture of the Rand Senantiomers of warfarinThe Senantiomer exhibits 2 to 5 times more anticoagulant activity than the R-enantiomer in humansbut generally has a more rapid clearance.

Frequency not reportedCerebral hemorrhagecerebral subdural hematomalethargyheadachedizzinesstaste perversionparesthesiaRef]

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