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admin     07 أكتوبر,2018         لا تعليق

Talk to your doctor right away about any side effects or other unusual symptoms that occur when taking epivir-hbv.

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Information about Epivir-HBV.

Epivir-HBV is not FDA approved for treatment of HIV-1 infectionlamivudine dosage in EPIVIR-HBV is subtherapeutic and monotherapy is inappropriate for the treatment of HIV-1 infection and the safety and efficacy of this drug have not been established in patients co-infected with HBV and HIVsevere acute exacerbations of hepatitis B reported in patients who have discontinued anti-hepatitis B therapyincluding HBV formulationhepatic function should be monitored closely with both clinical and laboratory follow-up for at least several months in patients who discontinue anti-hepatitis B therapyif appropriateinitiation of anti-hepatitis B therapy may be warranted.

Read the Patient Information Leaflet provided by your pharmacist before you start using lamivudine-HBV and each time you get a refillIf you have any questions regarding the informationconsult your doctor or pharmacist.

Coadministration of single doses of lamivudine and sorbitol resulted in a sorbitol dose-dependent reduction in lamivudine exposuresWhen possibleavoid use of sorbitol-containing medicines with lamivudinesee Clinical Pharmacology12.3Consider more frequent monitoring of HBV viral load when chronic coadministration cannot be avoided.

Risk of HIV-1 Resistance if Epivir-HBV is Used in Patients with Unrecognized or Untreated HIV-1 Infection.

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assessmentstudy 1study 2study 3epivir-hbv n 62 placebo n 63 epivir-hbv n 131 placebo n 68 epivir-hbv n 110 placebo n 54 improvementa55 25 56 26 56 26 no improvement27 59 36 62 25 54 missing data18 16 8 12 19 20 .

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