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Calcium channel blockers such as cardizem or tiazac diltiazem , covera hs or isoptin sr verapamil , and others.

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Inhalation AnestheticsAnimal experiments have shown that inhalation anesthetics depress cardiovascular activity by decreasing the inward movement of calcium ionsWhen used concomitantlyinhalation anesthetics and calcium antagonistssuch as verapamilshould each be titrated carefully to avoid excessive cardiovascular depression.

Verapamil was not mutagenic in the Ames test in 5 test strains at 3 mg per platewith or without metabolic activation.

ISOPTIN regularly reduces the total systemic resistanceafterloadagainst which the heart works both at rest and at a given level of exercise by dilating peripheral arterioles.

Some products that may interact with this drug includealiskirenclonidinedisopyramidedofetilidedolasetronfingolimodlithium.

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