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Before initiating treatment with SINEMETadvise patients about the potential to develop drowsiness and ask specifically about factors that may increase the risk for somnolence with SINEMET such as the use of concomitant sedating medications and the presence of sleep disordersConsider discontinuing SINEMET in patients who report significant daytime sleepiness or episodes of falling asleep during activities that require active participatione.gconversationseatingetcIf treatment with SINEMET continuespatients should be advised not to drive and to avoid other potentially dangerous activities that might result in harm if the patients become somnolentThere is insufficient information to establish that dose reduction will eliminate episodes of falling asleep while engaged in activities of daily living.

The patient should be advised that a change in diet to foods that are high in protein may delay the absorption of levodopa and may reduce the amount taken up in the circulationExcessive acidity also delays stomach emptyingthus delaying the absorption of levodopaIron saltssuch as in multivitamin tabletsmay also reduce the amount How much neurontin cost of levodopa available to the bodyThe above factors may reduce the clinical effectiveness of the levodopa or carbidopa levodopa therapy.

SINEMET helps most people with Parkinson’s diseasebut it may have unwanted side effects in a few peopleAll medicines can have side effectsSometimes they are seriousmost of the time they are notYou may need medical treatment if you get some of the side effects.

SINEMET is contraindicated in patients with known hypersensitivity to any component of this drugand in patients with narrow-angle glaucoma.

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