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Now 18 months after xeloda i occasionally get the stabbing pain in one foot but it lasts only about 10-30 seconds and does get your attension.

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Table 19 Response Rates in Doubly-Resistant Patients Single-Arm Breast Cancer Trial.

XELODA dosage may need to be individualized to optimize patient managementPatients should be carefully monitored for toxicity and doses of XELODA should be modified as necessary to accommodate individual patient tolerance to treatmentsee Clinical StudiesToxicity due to XELODA administration may be managed by symptomatic treatmentdose interruptions and adjustment of XELODA doseOnce the dose has been reducedit should not be increased at a later timeDoses of XELODA omitted for toxicity are not replaced or restoredinstead the patient should resume the planned treatment cycles.

The level of phenytoin should be carefully monitored in patients taking XELODA and phenytoin dose may need to be reducedsee DOSAGE AND ADMINISTRATIONPostmarketing reports indicate that some patients receiving XELODA and phenytoin had toxicity associated with elevated phenytoin levelsFormal drug-drug interaction studies with phenytoin have not been conductedbut the Dapoxetine price philippines mechanism of interaction is presumed to be inhibition of the CYP2C9 isoenzyme by capecitabine and/or its metabolites.

Physicians should exercise caution in monitoring the effects of XELODA in the elderlyInsufficient data are available to provide a dosage recommendation.

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single doses of xeloda were not lethal to mice, rats, and monkeys at doses up to 2000 mg kg 2.

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