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Celebrex accounted for 14 of the new prescriptions in late september, but again according to impact rx this number has dropped to 11 .

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Additionallyfluid retention and edema have been observed in some patients treated with NSAIDsUse of celecoxib may blunt the CV effects of several therapeutic agents used to treat these medical conditionse.gdiureticsACE inhibitorsor angiotensin receptor blockersARBssee DRUG INTERACTIONS

NSAIDsincluding CELEBREX can lead to new onset of hypertension or worsening of preexisting hypertensioneither of which may contribute to the increased incidence of CV eventsPatients taking angiotensin converting enzymeACEinhibitorsthiazide diuretics or loop diuretics may have impaired response to these therapies when taking NSAIDssee DRUG INTERACTIONS

Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.

Read all patient informationmedication guidesand instruction sheets provided to youAsk your doctor or pharmacist if you have any questions.

Use the lowest effective dosage for the shortest possible durationAvoid administration of more than one NSAID at a timeAvoid use in patients at higher risk unless benefits are expected to outweigh the increased risk of bleedingFor such patientsas well as those with active GI bleedingconsider alternate therapies other than NSAIDsRemain alert for signs and symptoms of GI ulceration and bleeding during NSAID therapyIf a serious GI adverse event is suspectedpromptly initiate evaluation and treatmentand discontinue CELEBREX until a serious Caravans for sale benicarlo GI adverse event is ruled outIn the setting of concomitant use of low-dose aspirin for cardiac prophylaxismonitor patients more closely for evidence of GI bleedingsee DRUG INTERACTIONS

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there are certain serious risks associated with celebrex and other nsaids.

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