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This drug may be used as part of a combination therapyThat means you need to take it with other drugs.
CholestyramineQuestranand colestipolColestidmay decrease the absorption of indomethacin by binding to indomethacin in the intestine and preventing absorption into the bodyIndomethacin and other NSAIDs may decrease the elimination of lithiumEskalithLithobidby the kidneys andthereforeincrease the blood level of lithiumwhich could lead to lithium toxicity.
Indomethacin can increase your risk of fatal heart attack or strokeespecially if you use it long term or take high dosesor if you have heart diseaseDo not use indomethacin just before or after heart bypass surgerycoronary artery bypass graftor CABG
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